Ozone, the triatomic form of oxygen, at room temperature is a gas and is present in the various layers of the atmosphere with different concentrations. It is formed in the troposphere as a result of the action of ultraviolet rays on oxygen according to the following reaction:

O2 + hv = O + O

O + O2 = O3

It is a highly unstable, blue coloured gas with a characteristic sharp odour. Thanks to its ability to absorb ultraviolet rays, ozone is indispensible to life on earth. However, in addition to its eco-protective effect it has oxidizing properties that are even stronger than those of oxygen; although harmful in very high doses, at low concentrations ozone exerts very interesting properties as it easily releases active oxygen. In the industrial field it is employed especially for its disinfectant and clarifying properties.

At the end of the 19th century it was shown that ozone is able to oxidize a wide range of double bond organic compounds by destroying different toxic and/or harmful substances and inactivating bacterial contaminants.

As early as 1870 in Germany its biological properties were used for therapeutic purposes, for blood purification, treatment of anemia, diabetes, ulcerations, asthma.

Over the years ozone-therapy became increasingly widespread thanks to the good results obtained in the treatment of vascular-related and immunity-related pathologies.